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Research shows they can lower systolic blood pressure by 2 to 10 mmHg on average, with tirzepatide showing the strongest effects

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The consensus among diabetes specialists is that semaglutide is not contraindicated in Type 1 diabetes but should only be considered for patients with body mass index (BMI) above 27 kg/m² who have failed other weight loss methods and who have access to an endocrinologist experienced in insulin adjustment